Future-Proofing Lab Operations: The Benefits of SaaS Laboratory Information Systems

Modern laboratories face several challenges. These include complex workflows, stringent compliance requirements, increasing data volumes, and the need for efficient collaboration. Enter SaaS Laboratory Information Systems (LIS). They offer the promise of streamlined operations, improved productivity, and enhanced scalability. Most importantly, they future-proof lab operations against changing technology landscapes.

What Are SaaS Laboratory Information Systems?

SaaS Laboratory Information Systems, or SaaS LIS, operate through the cloud. Service providers host and upkeep the LIS applications on their servers. Users from laboratories can use these applications via the internet. This use minimizes the need for onsite software installations, hardware, and complex IT infrastructure. These services typically follow a subscription model. A recurring fee covers service maintenance and routine updates.

Laboratories are strategically shifting their operations. This shift moves from conventional LIS solutions to SaaS LIS. This change is in line with the broader digital transformation trend. This trend is prominent across various sectors. Traditional systems often struggle to keep up with fast-paced data landscapes and complex workflows. Thus, laboratories are increasingly recognizing the value of SaaS LIS.

Why Laboratories Should Consider SaaS Laboratory Information Systems

Operational Efficiency

At the heart of SaaS LIS lies the capability to streamline lab operations. The systems offer a wide variety of features, such as sample tracking, data management, and automation of repetitive tasks, enabling laboratories to enhance their operational efficiency and overall productivity.


Scalability is a significant advantage offered by SaaS LIS. As labs expand, they generate more data and require more processing capabilities. Unlike traditional systems that would need additional hardware or software installations, SaaS LIS can comfortably accommodate this growth.

Cost Savings

SaaS LIS can help laboratories achieve substantial cost savings. Expenses related to IT infrastructure, software installations, and updates can be eliminated, and the subscription-based model allows for predictable budgeting.

Improved Collaboration

SaaS LIS can greatly improve collaboration between lab personnel. It allows for the sharing and accessing of information from any location, at any time, which is particularly beneficial for remote and multi-site lab operations.

Automated Compliance

Compliance with regulatory mandates is a critical component of lab operations, and SaaS LIS simplifies this aspect by automating compliance-related tasks. The systems generate audit trails, flag anomalies, and maintain necessary records, ensuring compliance is integral to your operations, not an add-on.

Data Security and Privacy

In the laboratory environment, data security and privacy are of paramount importance. SaaS LIS providers deploy robust security measures, including data encryption, secure user access, and routine security audits to safeguard sensitive information.

There are also other advantages of this system, which you can learn through this dedicated guide to LIS benefits.

Choosing a SaaS Laboratory Information System

The process of selecting a suitable SaaS LIS should be strategic, considering the following:

Feature Set and Functionality: The chosen system should align with your lab’s specific needs. Important features to consider include sample tracking, data management, workflow automation, and compliance support.

Integration Capability: Integration with other systems in your lab is essential for seamless data flow and optimized operational efficiency. Ensure the selected LIS can integrate smoothly with existing systems.

Vendor Support: Vendor support is a vital factor in choosing a SaaS LIS. Opt for vendors who offer reliable support, regular updates, and prompt problem resolution.

Cost: While cost is always an important consideration, it should not be at the expense of system quality or performance.

Scalability: As your lab grows, your chosen LIS should be able to scale to meet increasing data volumes and processing needs without significant additional investment.

SaaS Laboratory Information Systems: Use Cases

There are several use cases of SaaS LIS. For example, those who implement it benefit from:

Use Case 1: Streamlining Workflow Management

Consider a medium-sized diagnostic laboratory. It processes hundreds of samples each day. Managing these samples with efficiency and accuracy poses a significant challenge. A SaaS LIS can come to the rescue here. It automates the laboratory’s workflow—from specimen collection to result delivery. The system generates a unique barcode for each sample. This practice reduces the chance of errors significantly. It promotes smooth functioning within the lab and reduces turnaround time.

Use Case 2: Enabling Real-Time Access to Data

A pharmaceutical research lab often juggles several projects simultaneously. Teams require real-time access to data to drive informed decisions. A SaaS LIS delivers on this requirement. It allows scientists to access, analyze, and share data across different projects in real time. The result? Enhanced collaboration between teams, accelerating the discovery process.

Use Case 3: Facilitating Compliance and Audit Requirements

Clinical labs face numerous regulations. These include the Clinical Laboratory Improvement Amendments (CLIA) and Health Insurance Portability and Accountability Act (HIPAA). A SaaS LIS simplifies the compliance process. It generates comprehensive reports for audit trails. It also helps labs maintain records per regulatory standards. In doing so, it helps labs meet regulatory compliance more effectively.

Use Case 4: Assisting in Resource Optimization

Let’s take a biochemistry lab in an academic institution. Here, resources are often limited. A SaaS LIS can support in optimizing resource utilization. By reviewing past data, it can predict future resource requirements. This insight supports planning. The system identifies bottlenecks in operations and suggests improvements. This not only curtails costs but also enhances productivity.

Use Case 5: Boosting Patient-Centric Services

Take the case of a hospital lab that needs to provide patient-centric services. With a SaaS Laboratory Information System, patients can access their laboratory results online through a secure portal. This setup allows them to monitor their health proactively and make informed decisions. By facilitating direct patient access to lab results, the SaaS LIS empowers patients in their healthcare journey, fostering a culture of transparency and engagement. This approach significantly enhances the overall patient experience, leading to improved satisfaction and loyalty.

Current State of Laboratory Information Systems

Price often guides a laboratory’s choice for a Laboratory Information Management System (LIS). Many vendors suggest that SaaS-based LIS could result in significant savings compared to an on-site solution. This calculation considers the average seven-year lifespan of a LIS before a significant upgrade or replacement. It also factors in the yearly costs associated with hardware and IT resources.

However, cost should not be the sole deciding factor. The initial questions a decision-maker should pose are, “What do we need?” and “Why do we need it?” The answers will direct various scenarios in which a SaaS-based LIS may be the most suitable.

For instance, a technologically adept organization already leveraging the cloud will find the answer to “why” relatively easy. Especially if the executive team has decided to shift towards a cloud-first strategy. Similarly, establishments with limited IT and financial resources might view a cloud-based solution as an ideal match for their requirements.

Another scenario where the SaaS model thrives is in labs of all sizes that perform simple or routine tasks. These labs may not require a full-featured or fully configured informatics suite.

Moreover, periods of mergers and acquisitions, contract projects, off-shore projects, or other transitional periods might need temporary solutions. In such instances, where the feature set required for long-term use is unclear, a subscription-based LIS shines. It offers inbuilt security, flexibility, scalability, and ease of adoption

Top LIS Systems In The Market


LabWare LIS is a flexible platform designed to meet the diverse needs of modern laboratories. It offers an extensive suite of tools for automating and streamlining lab processes. Its capabilities include sample management, data analysis, quality control, and compliance tracking.


LabVantage offers robust capabilities to optimize lab efficiency. It provides functionalities like workflow automation, data capture, reporting, and regulatory compliance. The platform is scalable, suiting labs of various sizes and operational complexity.


STARLIS is a comprehensive solution that merges LIS, Electronic Laboratory Notebook (ELN), and Scientific Data Management System (SDMS) in one platform. It assists in managing complex processes, supporting regulatory compliance, and promoting laboratory efficiency.

Thermo Fisher SampleManager 

SampleManager from Thermo Fisher is a scalable solution built to enhance productivity. It features capabilities like data tracking, process automation, compliance management, and reporting. The platform supports seamless integration with other lab systems.


SoftLab is a robust LIS specifically for the clinical laboratory. It offers advanced workflow optimization tools, extensive reporting capabilities, and broad instrument compatibility. The system also includes options for improving patient safety and diagnostic accuracy.

Sunquest Information Systems 

Sunquest offers a wide range of laboratory informatics solutions, including robust LIS. Its platform aids in enhancing lab productivity and accuracy, managing complex workflows, and maintaining regulatory compliance. The system is adaptable, catering to diverse laboratory environments.

Steps to Implement a LIS

When the right LIS matches the organization’s goals, the next phase is implementation. The following steps offer guidance:

Step 1: Tailoring the LIS to Fit Specific Needs 

The first step involves understanding the key challenges hindering lab productivity. This could be anything from sample management, data collection to analysis. Next, comes the customization of the software to address these concerns effectively.

Step 2: Migrating Data 

Often, this step is time-intensive as it involves moving all existing data to the new LIS. Ensuring data security during this transition is paramount.

Step 3: User-Acceptance 

Testing The third step involves an extensive testing process. Each implemented phase of the LIS and the overall system needs thorough testing. This ensures the system works as intended.

Step 4: Staff Training 

Key personnel receive training from the LIS suppliers initially. Then, these staff members pass on the training to the rest of the team. This process ensures everyone has a good understanding of the system’s procedures and capabilities.

Step 5: Going Live 

When all the previous steps are complete, the LIS system can go live. At this point, the lab transitions entirely from old systems to the new LIS.

Step 6: Software Validation (Optional) 

For labs adhering to strict regulatory requirements, it might be necessary to validate the software. This step involves documenting the system’s specific requirements and testing each component to ensure it meets the requisite standards.

Software Validation

LMIS vs. ELN: Key Difference

LIS and ELN play distinct roles in a lab. LIS tracks samples, manages reports, and oversees workflow. It focuses on process and procedural control. On the flip side, ELN acts as a digital notepad. Scientists use it to capture and preserve research data, methodologies, and observations. Thus, LIS streamline procedures. ELNs safeguard and document scientific data. Both systems can work together. This teamwork contributes to the lab’s efficiency and data integrity.

What’s The Future of LIS?

LIS continues to play a pivotal role in modern labs. It supports workflows and mitigates the risk of human errors. Automated systems, from cell culture to genomics, are working in tandem with LIS. Together, they manage cell lines, monitor passages, and maintain a database of assays performed on cells, lysates, or DNA/RNA. This database is easily accessible to lab staff anywhere.

Growth and regulatory compliance require robust tools. LIS has proven to be such a tool. Thus, it will remain an integral part of lab operations. Cloud-based services, in particular, are gaining traction. They offer ease of access, cost efficiency, and robust data encryption. As we look to the future, we can expect cloud-based LIS to play a larger role.


Shaping lab operations for the future calls for agility, flexibility, and innovation. SaaS-based Laboratory Information Systems (LIS) bring these traits to the table. They redefine how labs function, making them more efficient and effective. Here’s a recap of their functionality and importance: 

  • SaaS LIS are cloud-based solutions that minimize the need for on-site installations and infrastructure.
  • The transition to SaaS LIS aligns with broader digital transformation trends across various sectors.
  • SaaS LIS increases efficiency, supports real-time access to data, and simplifies compliance.
  • They are cost-effective, reducing both capital expenses and operational costs.
  • Implementing a LIS involves configuration to specific needs, data transfer, user-acceptance testing, staff training, and possibly validation.
  • LIS differs from ELN. While LIS manages lab processes and workflow, ELN serves as a digital lab notebook for data recording.
  • Looking to the future, LIS will continue to revolutionize lab workflows, particularly with automated systems and cloud-based services.

Taking into account these considerations, it’s evident that SaaS-based LIS are not just a trend. They are a fundamental shift in the lab operations landscape. Adopting these systems can future-proof laboratory operations and open doors to unprecedented efficiency and agility.